What is the best way to deal with doubt and anxiety? In Philippians 4, the Apostle Paul says, “Do not be anxious about anything, but in every situation, by prayer and petition, with thanksgiving, present your requests to God. And the peace of God, which transcends all understanding, will guard your hearts and your minds in Christ Jesus” (Phil 4:6-7). In these passages, we learn that the best way to cope with doubt and anxiety is not mere suppression of negative thoughts, but substitution with noble ones. We will also learn what it means to sanctify our circumstances.